HIV/AIDS is a global health problem affecting women around the globe. The term global health refers to the goal of improving health and achieving equity in health for all people worldwide. HIV is a virus that destroys the immune system. AIDS is the last stage of the virus. During this stage there is little to no immune system left to fight off other infections or cancers. This virus can be acquired by men, women, and children of any age. HIV is the leading cause of death among women of reproductive age. This paper is an analytical review of research and literature related to the contributing factors to the rise of HIV in women, treatment and policy development. The model: Global Model: Gender Inequalities of Women Contributing to HIV Pandemic around the Globe was used in conceptualizing gender inequality and power imbalances between men and women contributing to the incidence and prevalence of HIV of women around the globe. Global health problems such as HIV/AIDs are best addressed by collaborate efforts and solutions that involve more than one country. More research is needed collaboratively on for the treatment of women around the globe. Collaborative efforts are needed for empowerment, improving treatment and educating women on HIV/AIDS Policy development is needed in changing laws to promote gender equality for women around the globe.